Saturday, 15 June 2019

PCSK9 inhibitors: Studies needed to prove efficacy and safety in chronic kidney disease

Chronic kidney disease (CKD) is associated with a substantially increased risk for the development of atherosclerotic cardiovascular disease (CVD). Accordingly, cardiovascular mortality is increased even in the earliest stages of CKD. In the general population and in CKD patients, high plasma levels of low-density lipoprotein cholesterol (LDL-C) are crucially involved in the initiation and progression of atherosclerotic vascular lesions. In addition, it has been documented that LDL accumulating in the vascular wall is prone to be post-translationally modified, for example, by oxidation or carbamylation, which is particularly relevant to patients with CKD.

* This article was originally published here

Controlling temperatures for inexpensive plant experiments

A study out of Clemson University has demonstrated that inexpensive, easy-to-use temperature controllers are able to provide reliable set temperatures for the detailed observation of developmental rates in response to different temperature treatments.

* This article was originally published here

The whisper of schizophrenia: Machine learning finds 'sound' words predict psychosis

A machine-learning method discovered a hidden clue in people's language predictive of the later emergence of psychosis—the frequent use of words associated with sound. A paper published by the journal npj Schizophrenia published the findings by scientists at Emory University and Harvard University.

* This article was originally published here

Holistic view of planning energy self-sufficient communities

Sustainable communities supplied by local renewable energy production are beginning to be established in the U.S. By using energy-efficient buildings and distributing means of energy generation, such as solar panels, throughout buildings in these districts, the communities manage to produce enough energy for their local needs—achieving a yearly net zero energy (NZE) balance.

* This article was originally published here

Urbach Tower offers view of self-shaping architecture

Oh, those leaning towers are so yesterday. Tech-watching sites, rather, are talking about a tower that does not lean; it is just as interesting as it is a self twisting tower. This is the Urbach Tower.

* This article was originally published here